{"id":4223,"date":"2026-11-07T09:16:53","date_gmt":"2026-11-07T09:16:53","guid":{"rendered":"https:\/\/nutricardio.ro\/?p=4223"},"modified":"2026-11-07T09:36:41","modified_gmt":"2026-11-07T09:36:41","slug":"ce-este-metabolismul-cu-un-singur-carbon","status":"publish","type":"post","link":"https:\/\/nutricardio.ro\/ce-este-metabolismul-cu-un-singur-carbon\/","title":{"rendered":"Ce este metabolismul cu un singur carbon?"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"4223\" class=\"elementor elementor-4223\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1057256 e-flex e-con-boxed e-con e-parent\" data-id=\"1057256\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-a0936ff elementor-widget elementor-widget-image\" data-id=\"a0936ff\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"800\" height=\"320\" src=\"https:\/\/nutricardio.ro\/wp-content\/uploads\/2026\/07\/ChatGPT-Image-Jul-19-2026-02_24_15-PM-1024x409.png\" class=\"attachment-large size-large wp-image-3755\" alt=\"Ce este metabolismul cu un singur carbon?\" srcset=\"https:\/\/nutricardio.ro\/wp-content\/uploads\/2026\/07\/ChatGPT-Image-Jul-19-2026-02_24_15-PM-1024x409.png 1024w, https:\/\/nutricardio.ro\/wp-content\/uploads\/2026\/07\/ChatGPT-Image-Jul-19-2026-02_24_15-PM-300x120.png 300w, https:\/\/nutricardio.ro\/wp-content\/uploads\/2026\/07\/ChatGPT-Image-Jul-19-2026-02_24_15-PM-768x307.png 768w, https:\/\/nutricardio.ro\/wp-content\/uploads\/2026\/07\/ChatGPT-Image-Jul-19-2026-02_24_15-PM-1536x614.png 1536w, https:\/\/nutricardio.ro\/wp-content\/uploads\/2026\/07\/ChatGPT-Image-Jul-19-2026-02_24_15-PM.png 1983w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-d144e42 e-flex e-con-boxed e-con e-parent\" data-id=\"d144e42\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-fceaa90 elementor-widget elementor-widget-heading\" data-id=\"fceaa90\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">CUM CONTRIBUIE ALIMENTA\u021aIA LA S\u0102N\u0102TATEA CELULAR\u0102 \u0218I LONGEVITATE<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-9c86687 e-flex e-con-boxed e-con e-parent\" data-id=\"9c86687\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-717e47a elementor-widget elementor-widget-text-editor\" data-id=\"717e47a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p data-pm-slice=\"1 1 []\">\u00cenainte de a vorbi despre longevitate, despre metilarea ADN-ului \u0219i despre lungimea telomerilor, este important s\u0103 \u00een\u021belegem ce \u00eenseamn\u0103 metabolismul cu un singur carbon \u0219i cum particip\u0103 alimenta\u021bia la reglarea acestui sistem metabolic.<\/p><p>De\u0219i denumirea poate p\u0103rea complicat\u0103, principiul este relativ simplu: organismul folose\u0219te anumite substan\u021be nutritive pentru a produce \u0219i transfera grup\u0103ri chimice necesare func\u021bion\u0103rii celulelor. Aceste reac\u021bii contribuie la formarea ADN-ului, la reglarea activit\u0103\u021bii genelor \u0219i la men\u021binerea echilibrului metabolic.<\/p><p>Cu alte cuvinte, ceea ce m\u00e2nc\u0103m nu furnizeaz\u0103 doar energie \u0219i proteine. Ofer\u0103 \u0219i nutrien\u021bii de care celulele au nevoie pentru a-\u0219i desf\u0103\u0219ura procesele biochimice.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-16a4aa0 e-flex e-con-boxed e-con e-parent\" data-id=\"16a4aa0\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-8a71350 elementor-widget elementor-widget-heading\" data-id=\"8a71350\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Ce este metabolismul cu un singur carbon?<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-65e47ec e-flex e-con-boxed e-con e-parent\" data-id=\"65e47ec\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6916f1a elementor-widget elementor-widget-text-editor\" data-id=\"6916f1a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p data-pm-slice=\"1 1 []\">Este o re\u021bea de reac\u021bii biochimice prin care organismul transfer\u0103 mici unit\u0103\u021bi de carbon \u00eentre molecule. Aceste transferuri sunt importante pentru mai multe procese, printre care:<\/p><ul data-spread=\"false\"><li><p>sinteza \u0219i repararea materialului genetic;<\/p><\/li><li><p>reglarea expresiei genelor;<\/p><\/li><li><p>metabolismul aminoacizilor;<\/p><\/li><li><p>producerea unor molecule implicate \u00een protec\u021bia celular\u0103.<\/p><\/li><\/ul><p>Dou\u0103 dintre componentele sale principale sunt ciclul folatului \u0219i ciclul metioninei. Acestea func\u021bioneaz\u0103 \u00eempreun\u0103 \u0219i depind de aportul unor nutrien\u021bi precum folatul, vitaminele B12, B6 \u0219i B2, colina, betaina \u0219i aminoacizii metionin\u0103, serin\u0103 \u0219i glicin\u0103.<\/p><p>Acesta este primul punct \u00een care alimenta\u021bia devine esen\u021bial\u0103: pentru ca aceste procese s\u0103 func\u021bioneze corespunz\u0103tor, organismul are nevoie de materii prime \u0219i cofactori nutri\u021bionali suficien\u021bi.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-5d5955b e-flex e-con-boxed e-con e-parent\" data-id=\"5d5955b\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e6a17f4 elementor-widget elementor-widget-heading\" data-id=\"e6a17f4\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Leg\u0103tura dintre alimenta\u021bie \u0219i metilarea ADN-ului<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-2ab6df9 e-flex e-con-boxed e-con e-parent\" data-id=\"2ab6df9\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1b05046 elementor-widget elementor-widget-text-editor\" data-id=\"1b05046\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p data-pm-slice=\"1 1 []\">Metilarea ADN-ului este unul dintre mecanismele prin care organismul regleaz\u0103 activitatea genelor. Nu modific\u0103 secven\u021ba ADN-ului, ci influen\u021beaz\u0103 modul \u00een care anumite gene sunt activate sau inhibate.<\/p><p>Pentru acest proces, organismul utilizeaz\u0103 o molecul\u0103 numit\u0103 SAM (S-adenozilmetionin\u0103), care furnizeaz\u0103 grup\u0103rile metil necesare.<\/p><p>Producerea \u0219i reciclarea SAM depind de func\u021bionarea metabolismului cu un singur carbon, iar acesta este influen\u021bat de aportul alimentar de folat, vitamina B12, colin\u0103, betain\u0103 \u0219i metionin\u0103.<\/p><p>Este important de \u00een\u021beles c\u0103 nu urm\u0103rim s\u0103 stimul\u0103m c\u00e2t mai mult metilarea ADN-ului. Organismul are nevoie de un echilibru, deoarece at\u00e2t excesul, c\u00e2t \u0219i deficitul unor procese de metilare pot avea consecin\u021be asupra regl\u0103rii genelor.<\/p><p>Prin urmare, obiectivul nutri\u021bional este sus\u021binerea func\u021bion\u0103rii normale a acestui sistem, nu maximizarea unei singure reac\u021bii biochimice.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ef261ee e-flex e-con-boxed e-con e-parent\" data-id=\"ef261ee\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-8ef68bc elementor-widget elementor-widget-heading\" data-id=\"8ef68bc\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">De ce sunt importante glicina \u0219i metionina?<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-8e33ae1 e-flex e-con-boxed e-con e-parent\" data-id=\"8e33ae1\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-5b2b2ec elementor-widget elementor-widget-text-editor\" data-id=\"5b2b2ec\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p data-pm-slice=\"1 1 []\">Metionina este un aminoacid esen\u021bial, ob\u021binut prin alimenta\u021bie. Ea reprezint\u0103 punctul de plecare pentru producerea SAM, principalul donor de grup\u0103ri metil.<\/p><p>Glicina are un rol diferit, dar la fel de interesant. Particip\u0103 la reac\u021bii care ajut\u0103 organismul s\u0103 regleze utilizarea grup\u0103rilor metil \u0219i este necesar\u0103 pentru sinteza glutationului, creatinei \u0219i colagenului.<\/p><p>A\u0219adar, glicina nu este un donor direct de grup\u0103ri metil, dar contribuie la mai multe procese importante pentru func\u021bionarea celular\u0103.<\/p><p>Aceast\u0103 asociere este relevant\u0103 \u0219i din perspectiva nutri\u021biei: nu este suficient s\u0103 analiz\u0103m separat aportul de proteine. Conteaz\u0103 \u0219i compozi\u021bia lor \u00een aminoacizi \u0219i modul \u00een care ace\u0219tia particip\u0103 la procesele metabolice.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-adec823 e-flex e-con-boxed e-con e-parent\" data-id=\"adec823\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-0ad64f9 elementor-widget elementor-widget-heading\" data-id=\"0ad64f9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Ce leg\u0103tur\u0103 exist\u0103 cu longevitatea celular\u0103?<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-d9d532d e-flex e-con-boxed e-con e-parent\" data-id=\"d9d532d\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c13dc64 elementor-widget elementor-widget-text-editor\" data-id=\"c13dc64\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p data-pm-slice=\"1 1 []\">Metabolismul cu un singur carbon sus\u021bine procese fundamentale pentru men\u021binerea celulelor:<\/p><ul data-spread=\"false\"><li><p>contribuie la sinteza ADN-ului;<\/p><\/li><li><p>particip\u0103 la reglarea expresiei genelor;<\/p><\/li><li><p>sus\u021bine metabolismul aminoacizilor;<\/p><\/li><li><p>contribuie indirect la producerea glutationului, un antioxidant important;<\/p><\/li><li><p>particip\u0103 la men\u021binerea echilibrului metabolic celular.<\/p><\/li><\/ul><p>Aceste procese sunt relevante pentru s\u0103n\u0103tatea pe termen lung. Totu\u0219i, nu putem afirma c\u0103 un anumit aliment sau supliment prelunge\u0219te direct via\u021ba ori \u00eencetine\u0219te \u00eemb\u0103tr\u00e2nirea.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-760385c e-flex e-con-boxed e-con e-parent\" data-id=\"760385c\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-9905514 elementor-widget elementor-widget-heading\" data-id=\"9905514\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\">Unde intervine abordarea NutriCardio?<\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-50b2b86 e-flex e-con-boxed e-con e-parent\" data-id=\"50b2b86\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-cbb64ef elementor-widget elementor-widget-text-editor\" data-id=\"cbb64ef\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p data-pm-slice=\"1 1 []\">\u00cen nutri\u021bia clinic\u0103, alimenta\u021bia trebuie privit\u0103 dincolo de num\u0103rul de calorii \u0219i distribu\u021bia proteinelor, gr\u0103similor \u0219i carbohidra\u021bilor.<\/p><p>Un plan alimentar trebuie s\u0103 asigure \u0219i nutrien\u021bii necesari reac\u021biilor biochimice care sus\u021bin func\u021bionarea organismului.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ded01dd e-flex e-con-boxed e-con e-parent\" data-id=\"ded01dd\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-87d07ec elementor-widget elementor-widget-heading\" data-id=\"87d07ec\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Nutri\u021bia ca investi\u021bie \u00een s\u0103n\u0103tatea pe termen lung<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-9d4df05 e-flex e-con-boxed e-con e-parent\" data-id=\"9d4df05\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-867f639 elementor-widget elementor-widget-text-editor\" data-id=\"867f639\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p data-pm-slice=\"1 1 []\">Metabolismul cu un singur carbon ne arat\u0103 c\u00e2t de str\u00e2ns sunt legate alimenta\u021bia, func\u021bionarea genelor \u0219i procesele celulare.<\/p><p>Nu exist\u0103 un aliment-minune care s\u0103 controleze metilarea ADN-ului sau s\u0103 garanteze longevitatea. Exist\u0103 \u00eens\u0103 o multitudine de reac\u021bii biochimice care depind de nutrien\u021bii furniza\u021bi prin alimenta\u021bie.<\/p><p>\u00cen\u021belegerea acestor mecanisme ne permite s\u0103 construim strategii alimentare mai bine fundamentate, adaptate nevoilor organismului \u0219i obiectivelor individuale.<\/p><p><strong>La NutriCardio, abord\u0103m nutri\u021bia prin prisma fiziologiei, biochimiei \u0219i particularit\u0103\u021bilor metabolice individuale. Obiectivul nu este doar schimbarea greut\u0103\u021bii corporale, ci sus\u021binerea s\u0103n\u0103t\u0103\u021bii metabolice, a func\u021biei celulare, a performan\u021bei \u0219i a longevit\u0103\u021bii active.<\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-2d16e92 e-flex e-con-boxed e-con e-parent\" data-id=\"2d16e92\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-be5fc72 elementor-widget elementor-widget-image\" data-id=\"be5fc72\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t<figure class=\"wp-caption\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/nutricardio.ro\/contact\/\" target=\"_blank\">\n\t\t\t\t\t\t\t<img decoding=\"async\" width=\"205\" height=\"80\" src=\"https:\/\/nutricardio.ro\/wp-content\/uploads\/2025\/05\/contact.png\" class=\"attachment-large size-large wp-image-1815\" alt=\"\" \/>\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<figcaption class=\"widget-image-caption wp-caption-text\">Programeaz\u0103 o evaluare ini\u021bial\u0103 \u0219i construim \u00eempreun\u0103 o strategie adaptat\u0103 metabolismului t\u0103u.<\/figcaption>\n\t\t\t\t\t\t\t\t\t\t<\/figure>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-aa0292f e-flex e-con-boxed e-con e-parent\" data-id=\"aa0292f\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-5be631e elementor-widget elementor-widget-text-editor\" data-id=\"5be631e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p data-pm-slice=\"1 3 []\"><strong>Bibliografie \u0219tiin\u021bific\u0103 selectiv\u0103<\/strong><\/p><ul data-spread=\"false\"><li><p>Ducker GS, Rabinowitz JD. <em>One-Carbon Metabolism in Health and Disease.<\/em> Cell Metabolism. 2017;25(1):27\u201342. DOI: 10.1016\/j.cmet.2016.08.009.<\/p><\/li><li><p>Friso S et al. <em>One-carbon metabolism and epigenetics.<\/em> Molecular Aspects of Medicine. 2017.<\/p><\/li><li><p>Anderson OS et al. <em>Nutrition and epigenetics: an interplay of dietary methyl donors, one-carbon metabolism and DNA methylation.<\/em> Journal of Nutritional Biochemistry. 2012.<\/p><\/li><li><p>Horvath S, Raj K. <em>DNA methylation-based biomarkers and the epigenetic clock theory of ageing.<\/em> Nature Reviews Genetics. 2018;19:371\u2013384.<\/p><\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>CUM CONTRIBUIE ALIMENTA\u021aIA LA S\u0102N\u0102TATEA CELULAR\u0102 \u0218I LONGEVITATE \u00cenainte de a vorbi despre longevitate, despre metilarea ADN-ului \u0219i despre lungimea<\/p>\n","protected":false},"author":1,"featured_media":3755,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[870],"tags":[889,638,884,886,882,425,880,881,885,654,872,888,653,887,554,883],"class_list":["post-4223","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-protocolul-nutricardio","tag-alimentatie-si-longevitate","tag-epigenetica","tag-folat","tag-glicina","tag-longevitate-celulara","tag-metabolism-celular","tag-metabolism-cu-un-singur-carbon","tag-metilarea-adn-ului","tag-metionina","tag-nutrigenomica","tag-nutritie-clinica","tag-nutritie-integrativa","tag-nutritie-si-longevitate","tag-protocol-nutricardio","tag-sanatate-metabolica","tag-vitamine-b"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Ce este metabolismul cu un singur carbon? - Cabinet NutriCardio<\/title>\n<meta name=\"description\" content=\"Ce este metabolismul cu un singur carbon? 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